The timeslot allocated by CBS is a major question, although I did think of that in the context of it possibly being at least slightly scripted.
If they had attempted this during Bob and Roger's tenure, I would think there would be a higher chance they could perform a show that, if not a perfect 60 minutes, would come in at a fairly predictable runtime. The current crew runs things differently, and it works for them. It just poses more of an adjustment to make.
My point being, it's a big crapshoot what this could require. If CBS only budgets an hour and something goes catastrophically wrong, they're stuck with big overruns, but if they budget 90 minutes to two hours, it could end up working out smoothly and leaving a lot of time to be filled. It's going to require some very careful work and meticulous planning to figure out a slot that fits all scenarios.